Meclofenamic acid sodium salt,

Code: M4531-1G D2-231

Application

Meclofenamic acid sodium salt has been used:in the inhibition of heat-induced denaturation of albuminas a pharmacological agent in the preparation of superfusion ...


read more

Your Price
€50.31 1G
€61.88 inc. VAT

Application

Meclofenamic acid sodium salt has been used:in the inhibition of heat-induced denaturation of albuminas a pharmacological agent in the preparation of superfusion solution for electrophysiology studiesto block the gap junctions

Biochem/physiol Actions

Meclofenamic acid (MFA) is a nonsteroidal anti-inflammatory, analgesic and antipyretic drug. It inhibits prostaglandin biosynthesis pathway and finds its application in the treatment of postoperative and traumatic inflammation and swelling. MFA functions in opening the potassium voltage-gated channel subfamily Q member 2/member 3 (KCNQ2/Q3).

Cyclooxygenase (IC50 = 0.6 µM) and 5-lipoxygenase (IC50 = 46.3 µM) inhibitor.

Features and Benefits

This compound was developed by Pfizer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

General description

Meclofenamic acid consists of two aryl moieties that are twisted in perpendicular orientation, it includes N-2,6-dichloro-3-methylphenyl group and N-2-benzoic acid group. Because of the low aqueous solubility of the compound, it is commercially available as sodium salt.

Packaging

1, 5 g in glass bottle

assay≥93% (HPLC)
biological sourcesynthetic (organic)
formpowder
InChI keyCHGIZYUDGOIAFY-UHFFFAOYSA-N
InChI1S/C14H11Cl2NO2.Na.H/c1-8-6-7-10(15)13(12(8)16)17-11-5-3-2-4-9(11)14(18)19;;/h2-7,17H,1H3,(H,18,19);;
originatorPfizer
Quality Level100
SMILES string[Na].Cc1ccc(Cl)c(Nc2ccccc2C(O)=O)c1Cl
solubilitywater: 50 mg/mL, clear, colorless to very faintly brown, water: 50 mg/mL, clear, colorless to faintly brownish-yellow, water: 50 mg/mL, clear, colorless to faintly yellow
Cas Number6385-02-0
This product has met the following criteria to qualify for the following awards:



PROCEED TO CHECKOUT

HAVE AN ACCOUNT? LOGIN


GUEST CHECKOUT

Proceed as a guest. You will have the option to register to access exclusive pricing and stock availability features after checkout.